Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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AD Lung Beer Cluster Number 52 (67 genes) This page contains all miRNA mediated regulation and functional enrichment for AD Lung Beer cluster number 52. Information about lung cancer can be found on Wikipedia, and further information about the "AD Lung Beer" dataset can be found in Beer et al., 2002. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 hsa-mir-372 zzz999 Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0001775 cell activation 12 GO:0001952 regulation of cell-matrix adhesion 4 GO:0006140 regulation of nucleotide metabolic process 7 GO:0006171 cAMP biosynthetic process 6 GO:0006703 estrogen biosynthetic process 2 GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 5 GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger 5 GO:0009187 cyclic nucleotide metabolic process 6 GO:0009190 cyclic nucleotide biosynthetic process 6 GO:0019932 second-messenger-mediated signaling 8 GO:0019933 cAMP-mediated signaling 6 GO:0019935 cyclic-nucleotide-mediated signaling 6 GO:0030799 regulation of cyclic nucleotide metabolic process 6 GO:0030802 regulation of cyclic nucleotide biosynthetic process 6 GO:0030808 regulation of nucleotide biosynthetic process 6 GO:0030814 regulation of cAMP metabolic process 6 GO:0030817 regulation of cAMP biosynthetic process 6 GO:0031279 regulation of cyclase activity 5 GO:0042110 T cell activation 7 GO:0045321 leukocyte activation 9 GO:0045761 regulation of adenylate cyclase activity 5 GO:0046058 cAMP metabolic process 6 GO:0046649 lymphocyte activation 8 GO:0050790 regulation of catalytic activity 16 GO:0051339 regulation of lyase activity 5 GO:0065007 biological regulation 50 GO:0065008 regulation of biological quality 25 GO:0065009 regulation of molecular function 18 GO:0070228 regulation of lymphocyte apoptosis 3 GO:0070229 negative regulation of lymphocyte apoptosis 3 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-372 PITA GO:0001775 cell activation 2 12 67 8 0.1466254 hsa-mir-372 PITA GO:0001952 regulation of cell-matrix adhesion 1 4 67 8 0.06690586 hsa-mir-372 PITA GO:0006140 regulation of nucleotide metabolic process 3 7 67 8 0.002728811 hsa-mir-372 PITA GO:0006171 cAMP biosynthetic process 2 6 67 8 0.01947585 hsa-mir-372 PITA GO:0006703 estrogen biosynthetic process 0 2 67 8 0.226142 hsa-mir-372 PITA GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 1 5 67 8 0.1046066 hsa-mir-372 PITA GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger 1 5 67 8 0.1046066 hsa-mir-372 PITA GO:0009187 cyclic nucleotide metabolic process 2 6 67 8 0.01947585 hsa-mir-372 PITA GO:0009190 cyclic nucleotide biosynthetic process 2 6 67 8 0.01947585 hsa-mir-372 PITA GO:0019932 second-messenger-mediated signaling 1 8 67 8 0.2415834 hsa-mir-372 PITA GO:0019933 cAMP-mediated signaling 1 6 67 8 0.147172 hsa-mir-372 PITA GO:0019935 cyclic-nucleotide-mediated signaling 1 6 67 8 0.147172 hsa-mir-372 PITA GO:0030799 regulation of cyclic nucleotide metabolic process 2 6 67 8 0.01947585 hsa-mir-372 PITA GO:0030802 regulation of cyclic nucleotide biosynthetic process 2 6 67 8 0.01947585 hsa-mir-372 PITA GO:0030808 regulation of nucleotide biosynthetic process 2 6 67 8 0.01947585 hsa-mir-372 PITA GO:0030814 regulation of cAMP metabolic process 2 6 67 8 0.01947585 hsa-mir-372 PITA GO:0030817 regulation of cAMP biosynthetic process 2 6 67 8 0.01947585 hsa-mir-372 PITA GO:0031279 regulation of cyclase activity 1 5 67 8 0.1046066 hsa-mir-372 PITA GO:0042110 T cell activation 2 7 67 8 0.03203613 hsa-mir-372 PITA GO:0045321 leukocyte activation 2 9 67 8 0.06782583 hsa-mir-372 PITA GO:0045761 regulation of adenylate cyclase activity 1 5 67 8 0.1046066 hsa-mir-372 PITA GO:0046058 cAMP metabolic process 2 6 67 8 0.01947585 hsa-mir-372 PITA GO:0046649 lymphocyte activation 2 8 67 8 0.04815515 hsa-mir-372 PITA GO:0050790 regulation of catalytic activity 3 16 67 8 0.08533537 hsa-mir-372 PITA GO:0051339 regulation of lyase activity 1 5 67 8 0.1046066 hsa-mir-372 PITA GO:0065007 biological regulation 6 50 67 8 0.342654 hsa-mir-372 PITA GO:0065008 regulation of biological quality 3 25 67 8 0.33724 hsa-mir-372 PITA GO:0065009 regulation of molecular function 3 18 67 8 0.1271981 hsa-mir-372 PITA GO:0070228 regulation of lymphocyte apoptosis 1 3 67 8 0.0356539 hsa-mir-372 PITA GO:0070229 negative regulation of lymphocyte apoptosis 1 3 67 8 0.0356539

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